What is NAD+ Powder?
NAD+ Powder is solid, high-purity nicotinamide adenine dinucleotide (NAD+) in its powder form for use as an ingredient in industrial formulation and manufacturing applications. It is usually made by highly developed bio-fermentation or enzymatic synthesis and purification and drying processes in multiple stages to guarantee the consistency of quality, stability, and batch-to-batch uniformity. It is frequently used as an input ingredient in dietary supplement production, nutraceutical premix systems, cosmetic formulating, and biochemical research and lab applications. The material is standardized using a precisely controlled quality management program, including HPLC testing for purity to ensure adherence to manufacturers' specified ranges for purity. It is intended for use in capsule filling and packaging lines, tablet processing lines, powder blend processing lines, and liquid processing lines, depending on the production requirements downstream. It is often packaged in controlled moisture-resistant packaging to ensure stability during distribution, transportation, and storage. It is a functional raw material that can be used by formulators and contract manufacturers as they need a raw material that is consistent and can be used to make high-quality biochemical ingredients without being used for a final consumer product. It is popularly applied in ingredient supply chains all across the world, where traceability, production capacity, and regulatory documentation are important procurement considerations.

COA
| Test Item | Specification | Result |
| Appearance | White to off-white fine powder | Complies |
| Production Method | Enzymatic synthesis / fermentation-based process | Complies |
| Odor | Characteristic | Complies |
| Solubility | Soluble in water | Complies |
| Particle Size | ≥95% pass 80 mesh (or customized) | Complies |
| Moisture Content | ≤ 5.0% | 2.30% |
| pH (1% solution) | 2.0 – 3.5 | 2.8 |
| NAD+ Assay (HPLC) | ≥ 98.0% | 99.20% |
| Related Substances | ≤ 1.0% | 0.60% |
| Total Heavy Metals | ≤ 10 ppm | Complies |
| Lead (Pb) | ≤ 2 ppm | 0.5 ppm |
| Arsenic (As) | ≤ 1 ppm | 0.3 ppm |
| Cadmium (Cd) | ≤ 1 ppm | <0.1 ppm |
| Mercury (Hg) | ≤ 0.1 ppm | <0.05 ppm |
| Total Plate Count | ≤ 1,000 CFU/g | <100 CFU/g |
| Yeast & Mold | ≤ 100 CFU/g | <10 CFU/g |
| E. Coli | Negative | Negative |
| Salmonella | Negative | Negative |
| Staphylococcus Aureus | Negative | Negative |
| Ethanol | ≤ 5000 ppm | Complies |
| Methanol | ≤ 3000 ppm | Not detected |
| Acetone | ≤ 5000 ppm | Complies |
| GMO Status | Non-GMO | Complies |
| Additives | None | Complies |
| Shelf Life | 24 months | Complies |
| Packaging Type | Aluminum foil bag / fiber drum | Complies |
| Storage Condition | Cool, dry, light-protected | Complies |
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Origin Narrative
Enzymatic synthesis or multi-step biocatalytic conversion processes are generally used to build up the molecular structure of NAD+ in a tightly controlled manner, starting from selected precursor materials that are produced in controlled biochemical or fermentation processes. Following the synthesis steps, the material is subjected to a series of purification steps, such as filtration, decoloration, concentration, crystallization, and/or spray-drying, to produce a stable form of the material in powdered form and with defined physicochemical properties. A rigorous quality management programme is used throughout manufacturing to maintain consistency of the batch, such as maintaining controlled environmental conditions and in-process monitoring, and by analytical measurement (for example, HPLC) to verify the product identity and purity within the specified range. Depending on supplier capability and market needs, the Origin Narrative will also contain information on raw material sourcing, compliance of manufacturing sites, and compliance with known quality systems like GMP and ISO systems. After processing, Nicotinamide Adenine Dinucleotide Powder is packaged in a moisture-controlled and light-protective atmosphere for stability during storage and global trading.
Features
Pure NAD+ Powder is usually a fine powder with a high hygroscopic ability, which needs to be handled and stored under controlled humidity conditions in order to ensure that the physicochemical integrity is preserved. It is quite soluble in aqueous systems at the correct formulation conditions, although its stability will differ because of formulation pH, ionic strength, and processing temperature, and so formulation design is important for downstream use. On a chemical basis, NAD+ molecules contain the redox-active nicotinamide group as well as an adenine nucleotide structure, which makes it very sensitive and requires careful evaluation for compatibility when used in conjunction with other active ingredients, excipients, and carrier systems present in biochemical formulations. It is generally advised not to be exposed to high temperatures or alkali for too long in manufacturing and formulation processes, because this could affect the structural stability. It is flexible in its incorporation into capsule filling, dry blending, and controlled dispersion matrices, when necessary, using excipients for protection or incorporating into an encapsulating technology to enhance stability. It is usually provided in a narrow particle size range to ensure a consistent mixing behavior and flow properties in industrial processing applications.

Benefits
1. Standardized raw material supply
Ensures consistent specification control across batches that enables industrial formulation and large batch manufacturing systems to have predictable use.
2. Flexible formulation integration
Formulator-friendly, it can be used in a variety of dosages and delivery formats, including dry blends, encapsulated systems, and premix matrices, enabling formulators to tailor it to various product architectures.
3. Reliable quality verification support
Controlled by analytical documentation like COA and HPLC testing data, allowing effective incoming quality inspection & batch release process.
4. Improved process scalability
NAD Supplement Powder can be used in pilot-scale or commercial-scale production to enable manufacturers to move from R&D development to mass production.
5. Controlled handling characteristics
Process control parameters like particle size and moisture sensitivity management make processing more reliable in industrial equipment systems.
6. Supply chain traceability
Structured production and documentation systems enable clear tracking from upstream to downstream, contributing to procurement transparency and regulation alignment in markets.
7. Formulation compatibility adaptability
Can be added to various excipients and processing conditions as appropriate if formulation engineers use appropriate stabilization strategies.
8. Packaging and storage protection support
Supplied usually in moisture and light protective packages, which allow the material to be kept in good condition during transportation and long storage periods.
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