What is Superoxide Dismutase (SOD)?
Superoxide Dismutase (SOD) is a critical antioxidant enzyme naturally produced in the body that acts as a primary defense against cellular damage by breaking down harmful superoxide radicals into hydrogen peroxide and oxygen. It is used to combat oxidative stress, reduce inflammation, and in skincare to protect against environmental damage.
Everything You Need to Know
What is superoxide dismutase used for?
How to increase SOD in the body?
It has been recommended that consuming a diet high in fruits and vegetables that contain antioxidants helps increase SOD levels in the body. These nutrients include polyphenols, vitamin A, beta carotene, vitamin C, alpha-lipoic acid, etc.
What foods are high in superoxide dismutase?
The consumption of natural sources of SOD, such as cabbage, Brussels sprouts, wheatgrass, barley grass and broccoli has been encouraged . The use of SOD as a drug may be advantageous in terms of the quantity and duration of the pharmacological effect, compared to other antioxidants.
What diseases are linked to superoxide?
Superoxides have also been demonstrated to be an underlying cause in the pathophysiology of many diseases, such as cardiovascular disease, cancer, chronic inflammation, dementia, and amyotrophic lateral sclerosis, among others.
Main Details:
Antioxidant Defense: SOD constitutes the first line of defense against reactive oxygen species (ROS), protecting cells from superoxide toxicity.
Disease Management: SOD helps mitigate oxidative stress-related issues such as neurodegenerative diseases, inflammatory conditions, cancer, and diabetes.
Skin Health: It protects skin from UV radiation and pollution, reducing inflammation, redness, and signs of aging.
Anti-aging: By reducing superoxide accumulation, it is linked to increased longevity in studies involving organisms
Application
Medical uses
Supplementary superoxide dimutase has been suggested as a treatment to prevent bronchopulmonary dysplasia in infants who are born preterm, however, the effectiveness of his treatment is not clear.
Cosmetic uses
SOD may reduce free radical damage to skin-for example, to reduce fibrosis following radiation for breast cancer. Studies of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization, double-blinding, or placebo.Superoxide dismutase is known to reverse fibrosis, possibly through de-differentiation of myofibroblasts back to fibroblasts.
ANALYTICAL RESULTS
| Test Item | Method / Reference | Specification | Result | Conclusion | |
|---|---|---|---|---|---|
| Appearance | Visual | Light yellow to off-white powder | Light yellow powder | Conforms | |
| Odor | Organoleptic | Free of offensive odours | Complies | Conforms | |
| Enzyme Activity (SOD) | Spectrophotometric / Xanthine Oxidase coupled assay; unit definition aligned with common commercial practice | ≥ 20,000 U/g | 23,480 U/g | Conforms | |
| Mesh Size | Sieve analysis | 98% pass 80 mesh | 99.1% pass 80 mesh | Conforms | |
| Loss on Drying | 105°C / gravimetric | ≤ 8.0% | 4.7% | Conforms | |
| Loss on Ignition | Muffle furnace / gravimetric | ≤ 8.0% | 2.3% | Conforms | |
| Lead (Pb) | ICP-MS / ICP-OES | ≤ 3.0 ppm | 0.21 ppm | Conforms | |
| Cadmium (Cd) | ICP-MS / ICP-OES | ≤ 1.0 ppm | 0.05 ppm | Conforms | |
| Mercury (Hg) | ICP-MS / ICP-OES | ≤ 0.1 ppm | < 0.01 ppm | Conforms | |
| Arsenic (As) | ICP-MS / ICP-OES | ≤ 1.0 ppm | 0.08 ppm | Conforms | |
| Total Plate Count | USP <61> / plate count | < 10,000 CFU/g | 320 CFU/g | Conforms | |
| Yeast & Mold | USP <61> | < 100 CFU/g | < 10 CFU/g | Conforms | |
| E. coli | USP <62> | Not detected / 10 g | Not detected | Conforms | |
| Salmonella | USP <62> | Not detected / 10 g | Not detected | Conforms |
Production Process
